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William E. Schiesser’s book, Computational Chemotaxis Models for Neurodegenerative Disease, offers a comprehensive approach to assessing and understanding the complex dynamics of neurodegenerative diseases. The book is structured to provide a balanced overview of the relevant biology, physics, chemistry, and mathematics supporting the understanding of chemotaxis, a type of locomotion that relies on the intercellular, intermolecular transfer of neurotransmitters. It pays particular attention to the impact of changes in these processes on the development and progression of neurodegenerative diseases.The book begins with an introduction that examines the underlying principles of chemotaxis and then reviews the theoretical foundation of the field, including chemical and physical basis, diffusion, signal transduction, and cell motility. Readers are given a detailed overview of common types of neurodegenerative diseases, including Alzheimer's, Parkinson's, and Huntington's, and the role chemotaxis might play in their manifestations. This is followed by a review of mathematical and computational approaches used to study chemotaxis, as well as an overview of the various computer models that have been developed to simulate this process.The remainder of the book delves into the practical aspect of computational chemotaxis models. Schiesser’s material includes mathematical simulations of chemotaxis, application of the models to cellular behavior, and ways to apply the models to the study of neurodegenerative disease in general. Steps for using the models are outlined in detail, and concluding sections offer insights into how the models can be translated into clinical practice for ensuring accurate and reliable assessment of neurodegenerative diseases.The book also includes a review of the literature pertaining to the use of chemotaxis models in diagnosing and managing neurodegenerative diseases. It presents an in-depth exploration of the history, current trends, and future prospects of chemotaxis research in this field. This is invaluable to any reader looking to gain a comprehensive and authoritative understanding of the role that chemotaxis holds in the treatment and prevention of neurodegenerative diseases.William E. Schiesser’s Computational Chemotaxis Models for Neurodegenerative Disease is an invaluable resource for anyone interested in gaining a comprehensive understanding of the role that chemotaxis plays in the development and progression of neurodegenerative diseases. It thoroughly reviews the theories and principles underlying the field, while offering practical guidance on the use of chemotaxis models in the management of these disorders. As such, this book is essential reading for medical researchers and practitioners, bioengineers, and computer scientists who wish to apply their knowledge of chemotaxis to the study and treatment of neurodegenerative diseases. Computational Chemotaxis Models for Neurodegenerative Disease is a comprehensive, practical guide for researchers tackling the complexities of neurodegenerative diseases. In this book, professors William E. Schiesser and Ivo M. Ollerton explain how chemotaxis, or the movement of cells in response to chemical signals, can aid in understanding and battling conditions such as Alzheimer’s disease, Huntington’s disease, Parkinson’s disease, and amyotrophic lateral sclerosis (ALS).Schiesser and Ollerton discuss chemotaxis from a mathematical and computational perspective, emphasizing the development of novel chemotaxis models. These models can help researchers understand the mechanisms of neurodegenerative diseases and aid in the creation of effective treatments. The authors cover chemotaxis theory, model construction and analysis, as well as applications to neurodegenerative diseases.The book is a valuable resource for anyone with an interest in neurodegenerative diseases. It is loaded with equations, diagrams, and examples to illustrate the various mathematical models, making this an invaluable resource for both novice and experienced researchers. This is a great book for gaining a better understanding of chemotaxis and its role in neurodegenerative diseases, and it provides a wealth of insights into developing successful treatments. This book provides a comprehensive review of the current state of computational models for a wide range of neurodegenerative diseases, from Alzheimer’s, Parkinson’s, and Amyotrophic Lateral Sclerosis (ALS) to Huntington’s, schizophrenia, and even autism. In each chapter, the author, William E. Schiesser, examines the available evidence and develops an advanced computational model that can be used to better understand the dynamics of the underlying processes at a molecular level. He then reviews the most up-to-date findings concerning the disease, examining the roles of signal transduction pathways and the origin of pathogenetic mutations. The main focus of the book is on chemotaxis, or the cellular process of detecting and responding to chemical stimuli, which is of critical importance to the development of effective treatments for neurodegenerative diseases. Through mathematical and computational methods, the author analyzes the complex network of neuronal communication, examines the interplay between different cell types and the biochemical environment, and considers the influence of environmental factors such as temperature, pH, and hypoxia. The book reviews the concept of chemotaxis from a range of theoretical perspectives and considers the design of innovative experimental platforms for its study. This book is an invaluable resource for those looking for a comprehensive overview of the latest research into chemotaxis in the context of neurodegenerative diseases. Its clear, accessible writing style and extensive further reading suggests make it ideal for students of medicine, neuroscience, and mathematics, as well as anyone interested in learning more about the history, impact, and treatment of neurological diseases.

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